NBL1

Across TCGA patient cohorts, NBL1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,633 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NBL1-associated genes across cancer lineages are SFRP2, MYL9, and TSHZ3. Each is linked with NBL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both NBL1-to-partner and partner-to-NBL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NBL1 versus SFRP2 in OV, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBL1→partner) and Y-score (partner→NBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SFRP2 →	+2.999	+0.574	<.001	<.001	3	7
BRCA	MYL9 →	+1.037	+0.826	.001	.003	3	6
BRCA	TSHZ3 →	+0.871	+0.641	<.001	.008	3	6
OV	COL6A2 →	+1.524	+0.742	<.001	<.001	3	6
OV	FNDC1 →	+1.325	+0.682	<.001	.002	3	6
OV	RARRES2 →	+1.249	+0.672	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,633 associations by consensus.

NBL1 vs SFRP2 — OV

Explore this scatter interactively →