NBL1

Across TCGA cell cohorts, NBL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,041 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NBL1-associated GO terms across cancer lineages are Determination of dorsal identity, Determination of dorsal/ventral asymmetry, and Negative regulation of monocyte chemotaxis. Each is linked with NBL1 in more than 19 cancer types. Because this analysis shows association rather than direction, both NBL1-to-partner and partner-to-NBL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Determination of dorsal identity grouped by NBL1-low versus NBL1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NBL1→partner) and Y-score (partner→NBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Determination of dorsal identity →	+2.386	+4.448	<.001	<.001	3	20
BONE	Determination of dorsal/ventral asymmetry →	+0.416	+2.306	<.001	<.001	3	17
BLOOD_Lymphoma	Negative regulation of monocyte chemotaxis →	+0.911	+2.291	<.001	<.001	3	16
PANCREAS	Regulation of actin filament polymerization →	+0.116	+1.273	<.001	<.001	3	10
BONE	Response to manganese ion →	+0.148	+2.423	<.001	<.001	3	10
BONE	Negative regulation of cytokine production involved in inflammatory response →	+0.086	+1.640	.006	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,041 associations by consensus.

Determination of dorsal identity by NBL1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →