Q-omics provides the consensus-scored NBEAP4 profile across patient tissues and cancer cell-line models. NBEAP4 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, NBEAP4 is differentially expressed in 1, with the highest sampling consensus in THCA. Additionally, NBEAP4 RNA expression shows 6,754 significant gene co-expression associations, with the highest sampling consensus in SARC. Together, these results highlight MESO, THCA, and SARC as cancer lineages where NBEAP4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for NBEAP4 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes NBEAP4 survival associations across molecular data types. NBEAP4 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible NBEAP4 RNA expression–survival associations across cancer types. High NBEAP4 expression shows unfavorable associations in MESO, KICH, COAD, HNSC and KIRC, but favorable associations in UCS. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for NBEAP4 RNA expression.
This table summarizes NBEAP4 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for NBEAP4. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. NBEAP4 shows lower tumor expression in THCA. The THCA box plot shows higher NBEAP4 RNA expression in normal versus tumor tissue (log2 FC = −0.080, t-test p < 0.001).
This table shows molecular features associated with NBEAP4 in patient tissues and cancer cell lines. In patient samples, NBEAP4 shows the broadest associations at the RNA and protein expression levels, with SARC recurring as the lineage with the largest associated feature set.
