Across TCGA pan-cancer cohorts, NBEAP3 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of NBEAP3’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where NBEAP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NBEAP3 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

LUSC, BRCA, and LUAD are the cancer types where NBEAP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NBEAP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.014	<.001	4	view →
BRCA	All	II,III,IV	−0.011	.036	4	view →
LUAD	All	All	+0.010	.038	1	view →
THCA	All	All	+0.004	.014	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: NBEAP3 RNA expression & survival · all NBEAP3 data types