NBEAL2

Across TCGA cell cohorts, NBEAL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,287 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NBEAL2-associated GO terms across cancer lineages are Lactate metabolic process, Response to activity, and Regulation of metallopeptidase activity. Each is linked with NBEAL2 in more than 11 cancer types. Because this analysis shows association rather than direction, both NBEAL2-to-partner and partner-to-NBEAL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lactate metabolic process grouped by NBEAL2-low versus NBEAL2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NBEAL2→partner) and Y-score (partner→NBEAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Lactate metabolic process →	-0.180	-1.660	<.001	<.001	3	12
BONE	Response to activity →	-0.086	-1.368	<.001	<.001	3	11
BREAST	Regulation of metallopeptidase activity →	-0.250	-1.835	<.001	<.001	3	11
BREAST	Establishment of epithelial cell apical/basal polarity →	-0.191	-1.733	<.001	<.001	3	11
BONE	Pre-mRNA catabolic process →	+0.209	+1.454	<.001	<.001	3	10
BONE	Telomere organization →	+0.091	+1.545	.002	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,287 associations by consensus.

Lactate metabolic process by NBEAL2 expression — BREAST

Explore this box plot interactively →