NBEAL1

Across TCGA patient cohorts, NBEAL1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,270 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NBEAL1-associated genes across cancer lineages are GINS1, RAD51AP1, and ACRV1. Each is linked with NBEAL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both NBEAL1-to-partner and partner-to-NBEAL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NBEAL1 versus GINS1 in UCEC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBEAL1→partner) and Y-score (partner→NBEAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GINS1 →	-0.979	-0.343	<.001	<.001	3	6
UCEC	RAD51AP1 →	-1.213	-0.355	<.001	<.001	3	6
GBM	ACRV1 →	-0.934	-0.255	<.001	<.001	3	5
UCEC	FANCG →	-0.387	-0.374	.005	<.001	3	5
LSCC	POLA1 →	-0.748	-0.268	<.001	<.001	3	5
LSCC	SUV39H1 →	-0.635	-0.322	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,270 associations by consensus.

NBEAL1 vs GINS1 — UCEC

Explore this scatter interactively →