Across TCGA pan-cancer cohorts, NBDY mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated NBDY data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher NBDY mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NBDY expression acts as an unfavorable survival marker.

HNSC, LSCC, and PDAC are the cancer types where NBDY mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.185	0.858	.006	38	view →
LSCC	OS	Median	All	0.825	0.931	.026	3	view →
PDAC	OS	Tertile	III,IV	0.472	0.807	.034	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: NBDY tumor-vs-normal RNA expression · all NBDY data types