Across TCGA patient cohorts, NBDY mutation is significantly associated with the RNA expression of many other genes, with 506 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBDY-associated genes across cancer lineages are RPL23AP90, MIR98, and MAP3K4-AS1. Each is linked with NBDY in more than 1 cancer types. Because this analysis shows association rather than direction, both NBDY-to-partner and partner-to-NBDY results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBDY→partner) and Y-score (partner→NBDY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL23AP90 →	+0.433	+2.641	<.001	.005	3	1
UCEC	MIR98 →	+0.514	+3.538	<.001	<.001	3	1
UCEC	MAP3K4-AS1 →	+1.024	+3.330	<.001	.005	3	1
UCEC	STMN1P1 →	+0.430	+3.330	.006	.009	3	1
UCEC	MIR8071-2 →	+1.395	+2.906	<.001	.003	3	1
UCEC	TMPOP2 →	+0.478	+3.375	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 506 associations by consensus.

Exploration

NBDY survival (RNA) · tumor vs normal (RNA) · all NBDY data types