Across TCGA patient cohorts, NBDY mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBDY-associated genes across cancer lineages are CD8+ naive T-cells, Epithelial cells, and Endothelial cells. Each is linked with NBDY in more than 1 cancer types. Because this analysis shows association rather than direction, both NBDY-to-partner and partner-to-NBDY results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBDY→partner) and Y-score (partner→NBDY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.036	+2.212	.010	.034	3	1
UCEC	Epithelial cells →	-0.111	-3.161	.003	.019	3	1
UCEC	Endothelial cells →	-0.048	-3.279	.017	.011	2	1
UCEC	lymphatic Endothelial cells →	-0.025	-2.959	.043	.036	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

NBDY survival (RNA) · tumor vs normal (RNA) · all NBDY data types