Across TCGA cell cohorts, NAXD mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible NAXD-associated genes across cancer lineages are MAGEB4, C8A, and NPVF. Each is linked with NAXD in more than 1 cancer types. Because this analysis shows association rather than direction, both NAXD-to-partner and partner-to-NAXD results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAXD→partner) and Y-score (partner→NAXD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.019	+5.000	<.001	<.001	3	1
LARGE_INTESTINE	C8A →	+0.026	+3.684	<.001	.006	3	1
STOMACH	NPVF →	+0.020	+5.285	<.001	.003	3	1
STOMACH	KRTAP10-5 →	+0.036	+5.285	<.001	.003	3	1
BREAST	GFRA4 →	+0.022	+5.169	<.001	.005	3	1
BREAST	REG1B →	+1.039	+5.169	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

NAXD survival (RNA) · tumor vs normal (RNA) · all NAXD data types