NAV3

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NAV3 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NAV3 data layer compared with 22 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NAV3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NAV3 expression acts as an unfavorable survival marker.

LUAD and LSCC are the cancer types where NAV3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSTertileAll0.8271.000.02016view →
LSCCDFSTertileII,III,IV0.4960.905.0283view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

NAV3–LUAD (DFS)

Kaplan–Meier survival curve for NAV3 mass-spec protein-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration