NAV2

Across TCGA patient cohorts, NAV2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,268 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NAV2-associated genes across cancer lineages are PLLP, ASB2, and CD40LG. Each is linked with NAV2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NAV2-to-partner and partner-to-NAV2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAV2 versus PLLP in GBM, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAV2→partner) and Y-score (partner→NAV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLLP →	-0.888	-0.345	<.001	<.001	3	3
UCEC	ASB2 →	-0.823	-0.430	.001	.001	3	2
UCEC	CD40LG →	-0.598	-0.380	.007	<.001	3	2
UCEC	SYTL4 →	-0.718	-0.319	.002	.002	3	2
LUAD	ESRP1 →	+0.470	+0.249	<.001	.002	3	2
UCEC	PIK3CG →	-0.563	-0.489	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,268 associations by consensus.

NAV2 vs PLLP — GBM

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