NAV2

Across TCGA cell cohorts, NAV2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,895 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NAV2-associated GO terms across cancer lineages are Regulation of stress-activated MAPK cascade, Positive regulation of viral process, and Regulation of protein K48-linked ubiquitination. Each is linked with NAV2 in more than 10 cancer types. Because this analysis shows association rather than direction, both NAV2-to-partner and partner-to-NAV2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of stress-activated MAPK cascade grouped by NAV2-low versus NAV2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAV2→partner) and Y-score (partner→NAV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of stress-activated MAPK cascade →	+0.142	+2.372	.003	.001	3	11
STOMACH	Positive regulation of viral process →	+0.087	+2.718	.002	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of protein K48-linked ubiquitination →	+0.167	+1.394	.001	<.001	3	11
STOMACH	Regulation of protein modification by small protein conjugation or removal →	+0.064	+2.472	<.001	<.001	3	11
STOMACH	Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration →	+0.163	+2.244	<.001	<.001	3	11
BONE	Endocytic recycling →	+0.075	+2.136	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,895 associations by consensus.

Regulation of stress-activated MAPK cascade by NAV2 expression — LUNG_NSCLC_LUSC

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