NAV2

Across TCGA cell cohorts, NAV2 mutation is significantly associated with the RNA expression of many other genes, with 1,707 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NAV2-associated genes across cancer lineages are SUPT20HL1, UBE2S, and LONP1. Each is linked with NAV2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NAV2-to-partner and partner-to-NAV2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SUPT20HL1 grouped by NAV2-low versus NAV2-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAV2→partner) and Y-score (partner→NAV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	SUPT20HL1 →	+0.096	+4.807	<.001	.006	3	3
BLOOD_Leukemia	UBE2S →	+0.807	+3.214	.003	.006	3	3
LARGE_INTESTINE	LONP1 →	+0.775	+1.721	<.001	.003	3	3
BLOOD_Lymphoma	EEF2 →	+0.531	+3.321	.009	.006	3	3
LARGE_INTESTINE	SLC25A19 →	+0.517	+3.252	<.001	.002	3	3
LARGE_INTESTINE	C6orf52 →	+0.834	+2.628	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,707 associations by consensus.

SUPT20HL1 by NAV2 expression — BLOOD_Myeloma

Explore this box plot interactively →