NAV1

Across TCGA cell cohorts, NAV1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,815 significant associations in total. CNS shows the largest number of these associations.

The most reproducible NAV1-associated GO terms across cancer lineages are Regulation of intracellular protein transport, Regulation of protein K48-linked ubiquitination, and Positive regulation of intracellular transport. Each is linked with NAV1 in more than 12 cancer types. Because this analysis shows association rather than direction, both NAV1-to-partner and partner-to-NAV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular protein transport grouped by NAV1-low versus NAV1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAV1→partner) and Y-score (partner→NAV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of intracellular protein transport →	+0.064	+1.719	<.001	<.001	3	13
SKIN	Regulation of protein K48-linked ubiquitination →	+0.125	+1.238	<.001	<.001	3	12
BREAST	Positive regulation of intracellular transport →	+0.050	+1.327	<.001	.007	2	13
LIVER	Negative regulation of amino acid biosynthetic process →	+0.344	+2.796	<.001	<.001	3	11
LIVER	Negative regulation of amino acid metabolic process →	+0.344	+2.796	<.001	<.001	3	11
STOMACH	Cell motility involved in cerebral cortex radial glia guided migration →	+0.116	+2.109	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,815 associations by consensus.

Regulation of intracellular protein transport by NAV1 expression — LARGE_INTESTINE

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