NAT8

Across TCGA patient cohorts, NAT8 protein abundance is significantly associated with the RNA expression of many other genes, with 855 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible NAT8-associated genes across cancer lineages are LGALS2, RSPH14, and MIOX. Each is linked with NAT8 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAT8-to-partner and partner-to-NAT8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAT8 versus LGALS2 in CCRCC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAT8→partner) and Y-score (partner→NAT8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	LGALS2 →	+1.282	+0.456	<.001	<.001	3	1
CCRCC	RSPH14 →	+0.539	+0.413	<.001	<.001	3	1
CCRCC	MIOX →	+1.402	+0.340	<.001	<.001	3	1
CCRCC	HMGXB4 →	-0.207	-0.436	.005	<.001	3	1
CCRCC	CCDC198 →	+0.934	+0.486	.005	<.001	3	1
CCRCC	ADNP →	-0.200	-0.386	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 855 associations by consensus.

NAT8 vs LGALS2 — CCRCC

Explore this scatter interactively →