NAT8

Across TCGA cell cohorts, NAT8 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,917 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NAT8-associated GO terms across cancer lineages are Oocyte growth, Protein targeting to lysosome, and Catecholamine transport. Each is linked with NAT8 in more than 5 cancer types. Because this analysis shows association rather than direction, both NAT8-to-partner and partner-to-NAT8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oocyte growth grouped by NAT8-low versus NAT8-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAT8→partner) and Y-score (partner→NAT8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Oocyte growth →	+0.173	+0.172	<.001	.002	3	6
LUNG_SCLC	Protein targeting to lysosome →	+0.064	+0.170	.001	<.001	3	6
LIVER	Catecholamine transport →	+1.196	+2.190	.004	.005	3	5
LIVER	Chondroblast differentiation →	-1.451	-2.032	.003	.006	3	5
BONE	Cellular response to ATP →	+0.127	+0.081	<.001	.005	3	5
BONE	Regulation of glucose mediated signaling pathway →	+0.089	+0.080	.003	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,917 associations by consensus.

Oocyte growth by NAT8 expression — LUNG_SCLC

Explore this box plot interactively →