NAT1

Across TCGA patient cohorts, NAT1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,585 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NAT1-associated genes across cancer lineages are ASAH1, SH2D4A, and ERI1. Each is linked with NAT1 in more than 6 cancer types. Because this analysis shows association rather than direction, both NAT1-to-partner and partner-to-NAT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAT1 versus ASAH1 in BRCA, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAT1→partner) and Y-score (partner→NAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ASAH1 →	+1.051	+1.486	<.001	<.001	3	7
BRCA	SH2D4A →	+0.809	+1.092	<.001	<.001	2	7
OV	ERI1 →	+0.669	+0.387	<.001	<.001	3	6
BRCA	NUDT18 →	+0.830	+1.058	<.001	<.001	3	6
BRCA	FBP1 →	+1.566	+1.053	<.001	<.001	3	6
LSCC	NDRG4 →	-1.292	-0.411	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,585 associations by consensus.

NAT1 vs ASAH1 — BRCA

Explore this scatter interactively →