NAT1

Across TCGA cell cohorts, NAT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,604 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NAT1-associated GO terms across cancer lineages are Viral budding via host ESCRT complex, Multivesicular body organization, and Regulation of regulatory ncRNA-mediated heterochromatin formation. Each is linked with NAT1 in more than 12 cancer types. Because this analysis shows association rather than direction, both NAT1-to-partner and partner-to-NAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral budding via host ESCRT complex grouped by NAT1-low versus NAT1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAT1→partner) and Y-score (partner→NAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Viral budding via host ESCRT complex →	+0.100	+1.299	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Multivesicular body organization →	+0.085	+1.333	<.001	<.001	3	11
LIVER	Regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.122	+0.897	.002	<.001	3	10
LIVER	Negative regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.122	+0.897	.002	<.001	3	10
URINARY_TRACT	Multivesicular body assembly →	+0.090	+1.158	.001	<.001	2	11
SOFT_TISSUE	Endosome transport via multivesicular body sorting pathway →	+0.066	+1.104	.005	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,604 associations by consensus.

Viral budding via host ESCRT complex by NAT1 expression — SOFT_TISSUE

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