NASPP1

Across TCGA pan-cancer cohorts, NASPP1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of NASPP1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where NASPP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NASPP1 is over-expressed in tumor.

LUAD, BRCA, and COAD are the cancer types where NASPP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NASPP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	II,III,IV	+0.127	<.001	7	view →
BRCA	All	II,III,IV	+0.086	.001	6	view →
COAD	All	II,III,IV	+0.179	.001	5	view →
BLCA	All	All	+0.116	.024	5	view →
UCEC	All	All	+0.190	.011	4	view →
STAD	All	II,III,IV	+0.176	<.001	4	view →
CHOL	All	All	+0.100	.002	4	view →
LUSC	All	All	+0.099	.007	3	view →
KIRC	All	All	+0.019	.011	3	view →
LIHC	Male	All	+0.026	.014	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

NASPP1–LUAD

Open the LUAD breakdown →