NARS2

Across TCGA cell cohorts, NARS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,535 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NARS2-associated GO terms across cancer lineages are Asparaginyl-tRNA aminoacylation, Regulation of DNA stability, and Regulation of adaptive immune response. Each is linked with NARS2 in more than 19 cancer types. Because this analysis shows association rather than direction, both NARS2-to-partner and partner-to-NARS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Asparaginyl-tRNA aminoacylation grouped by NARS2-low versus NARS2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NARS2→partner) and Y-score (partner→NARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Asparaginyl-tRNA aminoacylation →	+0.186	+1.304	<.001	<.001	3	20
BLOOD_Myeloma	Regulation of DNA stability →	+0.182	+0.857	<.001	<.001	3	14
LIVER	Regulation of adaptive immune response →	-0.076	-0.637	<.001	.002	3	12
SOFT_TISSUE	Negative regulation of cell adhesion →	-0.072	-0.638	<.001	.001	3	12
CNS	Cellular response to molecule of bacterial origin →	-0.053	-0.663	<.001	<.001	3	12
SOFT_TISSUE	Fibroblast migration →	-0.156	-0.737	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,535 associations by consensus.

Asparaginyl-tRNA aminoacylation by NARS2 expression — SKIN

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