NARF

Across TCGA patient cohorts, NARF mutation is significantly associated with the RNA expression of many other genes, with 2,039 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NARF-associated genes across cancer lineages are RNU6-422P, RAD23A, and GNB1L. Each is linked with NARF in more than 1 cancer types. Because this analysis shows association rather than direction, both NARF-to-partner and partner-to-NARF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-422P grouped by NARF-low versus NARF-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NARF→partner) and Y-score (partner→NARF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-422P →	+0.438	+4.561	<.001	.005	3	2
UCEC	RAD23A →	+0.432	+2.684	.006	<.001	3	2
UCEC	GNB1L →	+0.342	+3.491	.009	.002	3	2
UCEC	RNU5E-1 →	+1.307	+2.506	<.001	.002	3	2
UCEC	RNA5SP393 →	+0.257	+2.252	<.001	.001	3	2
UCEC	RNA5SP415 →	+0.405	+2.073	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,039 associations by consensus.

RNU6-422P by NARF expression — LUSC

Explore this box plot interactively →