NARF-IT1

Across TCGA pan-cancer cohorts, NARF-IT1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated NARF-IT1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher NARF-IT1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated NARF-IT1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

HNSC, KIRC, and ACC are the cancer types where NARF-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.474	0.284	.001	97	view →
KIRC	DFS	Median	All	0.470	0.700	<.001	89	view →
ACC	DFS	Median	All	0.519	0.795	<.001	82	view →
UCS	DFS	Median	IV	0.952	0.367	.001	40	view →
PAAD	DFS	Quartile	II,III,IV	0.570	0.333	.002	37	view →
THCA	OS	Tertile	II,III,IV	0.892	0.990	.002	30	view →
LUSC	DFS	Quartile	II,III,IV	0.394	0.848	.003	27	view →
SKCM	DFS	Quartile	III,IV	0.638	0.324	.003	23	view →
PRAD	DFS	Tertile	All	0.822	0.930	.001	22	view →
MESO	DFS	Median	IV	0.181	0.443	.008	21	view →
BLCA	OS	Median	II,III,IV	0.654	0.555	.020	20	view →
PCPG	OS	Quartile	All	0.587	1.000	.013	19	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

NARF-IT1–HNSC (OS)

Open the HNSC breakdown →