NAPSB

Across TCGA patient cohorts, NAPSB RNA expression is significantly associated with the protein abundance of many other proteins, with 20,617 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NAPSB-associated proteins across cancer lineages are HCLS1, NFATC2, and SAMHD1. Each is linked with NAPSB in more than 9 cancer types. Because this analysis shows association rather than direction, both NAPSB-to-partner and partner-to-NAPSB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAPSB versus HCLS1 in GBM, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NAPSB→partner) and Y-score (partner→NAPSB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HCLS1 →	+0.697	+1.044	<.001	<.001	3	10
COAD	NFATC2 →	+0.618	+0.615	.001	.003	3	9
HNSC	SAMHD1 →	+0.567	+1.207	<.001	<.001	3	9
OV	SASH3 →	+0.531	+1.539	<.001	<.001	3	9
LSCC	SEPTIN1 →	+0.826	+1.004	<.001	<.001	3	9
HNSC	EVL →	+0.707	+1.268	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,617 associations by consensus.

NAPSB vs HCLS1 — GBM

Explore this scatter interactively →