NAPSB

Across TCGA patient cohorts, NAPSB protein abundance is significantly associated with the RNA expression of many other genes, with 9,030 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NAPSB-associated genes across cancer lineages are UBXN10, PLA2G2C, and SAMD15. Each is linked with NAPSB in more than 7 cancer types. Because this analysis shows association rather than direction, both NAPSB-to-partner and partner-to-NAPSB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAPSB versus UBXN10 in BRCA, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAPSB→partner) and Y-score (partner→NAPSB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UBXN10 →	+2.087	+0.884	<.001	<.001	3	8
BRCA	PLA2G2C →	+0.984	+0.828	<.001	<.001	3	6
BRCA	SAMD15 →	+1.468	+0.991	<.001	<.001	3	5
UCEC	CAPS →	+2.077	+1.002	<.001	<.001	3	5
BRCA	CEP126 →	+1.355	+0.832	<.001	<.001	3	5
CCRCC	TSPAN1 →	+1.593	+0.535	.009	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,030 associations by consensus.

NAPSB vs UBXN10 — BRCA

Explore this scatter interactively →