NAPSA

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NAPSA RNA expression is significantly associated with the protein abundance of many other proteins, with 18,023 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NAPSA-associated proteins across cancer lineages are SERBP1, NCL_S67, and INTS9_S572. Each is linked with NAPSA in more than 4 cancer types. Because this analysis shows association rather than direction, both NAPSA-to-partner and partner-to-NAPSA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAPSA versus SERBP1 in OV, with a Pearson correlation of -0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NAPSA→partner) and Y-score (partner→NAPSA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVSERBP1 →-0.330-0.744.001<.00135
LUADNCL_S67 →-0.819-1.514<.001<.00134
OVINTS9_S572 →-0.431-0.529.003.00934
OVMED26_S447 →-0.586-0.610<.001.00134
LUADSNX30 →+0.437+1.667<.001<.00134
GBMSPC24 →-0.530-0.299<.001.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,023 associations by consensus.

NAPSA vs SERBP1 — OV

Per-sample scatter of NAPSA vs SERBP1 in OV (Pearson r = -0.46).

Explore this scatter interactively →

Exploration