NAPSA

Across TCGA patient cohorts, NAPSA protein abundance is significantly associated with the RNA expression of many other genes, with 12,090 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NAPSA-associated genes across cancer lineages are PRR15L, GGTLC2, and COL4A3. Each is linked with NAPSA in more than 3 cancer types. Because this analysis shows association rather than direction, both NAPSA-to-partner and partner-to-NAPSA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAPSA versus PRR15L in CCRCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAPSA→partner) and Y-score (partner→NAPSA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PRR15L →	+1.983	+0.626	<.001	<.001	3	4
LUAD	GGTLC2 →	+0.372	+0.762	<.001	<.001	3	3
LSCC	COL4A3 →	+1.104	+0.847	<.001	<.001	3	3
LUAD	SHE →	+0.864	+0.675	<.001	<.001	3	3
LSCC	SFTA3 →	+2.052	+0.910	<.001	<.001	3	3
LSCC	LMO3 →	+1.244	+0.775	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,090 associations by consensus.

NAPSA vs PRR15L — CCRCC

Explore this scatter interactively →