NAPG

Across TCGA pan-cancer cohorts, NAPG mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated NAPG data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher NAPG mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NAPG expression acts as an unfavorable survival marker, although some lineages such as HNSC and PDAC show a favorable association.

HNSC, LSCC, and LUAD are the cancer types where NAPG mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	All	1.000	0.884	.015	20	view →
LSCC	OS	Tertile	III,IV	0.360	0.905	.001	14	view →
LUAD	OS	Quartile	All	0.617	0.893	.006	13	view →
PDAC	OS	Tertile	IV	0.973	0.443	.024	13	view →
UCEC	DFS	Tertile	All	0.953	0.794	.042	6	view →
GBM	DFS	Quartile	All	0.308	0.651	.004	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

NAPG–HNSC (DFS)

Open the HNSC breakdown →