NAPG

Across TCGA patient cohorts, NAPG mutation is significantly associated with the RNA expression of many other genes, with 1,369 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAPG-associated genes across cancer lineages are UBE2D3P4, RN7SL98P, and TRAJ11. Each is linked with NAPG in more than 1 cancer types. Because this analysis shows association rather than direction, both NAPG-to-partner and partner-to-NAPG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBE2D3P4 grouped by NAPG-low versus NAPG-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAPG→partner) and Y-score (partner→NAPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	UBE2D3P4 →	+0.074	+7.640	<.001	.009	3	2
COAD	RN7SL98P →	+0.258	+5.693	.001	.003	3	2
UCEC	TRAJ11 →	+0.407	+1.906	.002	.004	3	2
UCEC	EIF3JP1 →	+0.164	+2.198	<.001	.001	3	2
UCEC	KRT18P9 →	+0.138	+1.613	.005	.009	3	1
UCEC	CCL5 →	+0.882	+2.269	.008	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,369 associations by consensus.

UBE2D3P4 by NAPG expression — BLCA

Explore this box plot interactively →