NAPG

Across TCGA cell cohorts, NAPG mutation is significantly associated with the mutation status of many other genes, with 1,052 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NAPG-associated genes across cancer lineages are GALNT18, RINT1, and KAT6B. Each is linked with NAPG in more than 1 cancer types. Because this analysis shows association rather than direction, both NAPG-to-partner and partner-to-NAPG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALNT18 grouped by NAPG-low versus NAPG-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAPG→partner) and Y-score (partner→NAPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	GALNT18 →	+5.502	+5.502	.003	.003	1	2
LUNG_SCLC	RINT1 →	+5.502	+5.502	.003	.003	1	2
LARGE_INTESTINE	KAT6B →	+1.893	+3.865	.001	.001	1	2
LARGE_INTESTINE	KCNB1 →	+2.799	+4.635	<.001	<.001	1	2
LUNG_SCLC	PHC3 →	+5.502	+5.502	.003	.003	1	2
LARGE_INTESTINE	SLX4 →	+2.099	+4.064	.001	.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,052 associations by consensus.

GALNT18 by NAPG expression — LUNG_SCLC

Explore this box plot interactively →