NAPEPLD

Across TCGA cell cohorts, NAPEPLD mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NAPEPLD-associated genes across cancer lineages are FATE1, PNLIPRP3, and CFHR2. Each is linked with NAPEPLD in more than 1 cancer types. Because this analysis shows association rather than direction, both NAPEPLD-to-partner and partner-to-NAPEPLD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FATE1 grouped by NAPEPLD-low versus NAPEPLD-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAPEPLD→partner) and Y-score (partner→NAPEPLD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FATE1 →	+0.100	+3.551	<.001	.009	3	1
BLOOD_Leukemia	PNLIPRP3 →	+0.008	+3.551	.007	.009	3	1
BLOOD_Leukemia	CFHR2 →	+0.245	+5.124	<.001	<.001	3	1
LARGE_INTESTINE	SCRG1 →	+0.024	+3.793	.002	.007	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

FATE1 by NAPEPLD expression — BLOOD_Leukemia

Explore this box plot interactively →