NAPA

Across TCGA patient cohorts, NAPA RNA expression is significantly associated with the protein abundance of many other proteins, with 10,563 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NAPA-associated proteins across cancer lineages are ARHGAP35, NFIA, and PLOD1. Each is linked with NAPA in more than 4 cancer types. Because this analysis shows association rather than direction, both NAPA-to-partner and partner-to-NAPA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAPA versus ARHGAP35 in BRCA, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NAPA→partner) and Y-score (partner→NAPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARHGAP35 →	+0.414	+0.575	<.001	<.001	3	5
BRCA	NFIA →	+0.515	+0.740	.001	<.001	3	4
GBM	PLOD1 →	-0.411	-0.252	.005	.002	3	3
BRCA	NUP155 →	-0.176	-0.561	<.001	.001	3	3
LSCC	PRR11_S40 →	-0.684	-0.520	.002	<.001	3	3
OV	STRN4 →	+0.221	+0.505	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,563 associations by consensus.

NAPA vs ARHGAP35 — BRCA

Explore this scatter interactively →