Across TCGA patient cohorts, NAP1L4 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAP1L4-associated genes across cancer lineages are p27_pT198, ERK2, and Gab2. Each is linked with NAP1L4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAP1L4-to-partner and partner-to-NAP1L4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAP1L4→partner) and Y-score (partner→NAP1L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p27_pT198 →	+0.105	+3.321	.010	.010	3	2
UCEC	ERK2 →	+0.216	+2.700	.003	.006	3	1
UCEC	Gab2 →	+0.518	+3.700	<.001	.001	3	1
UCEC	JNK2 →	+0.175	+2.348	.022	.018	3	1
UCEC	MEK1 →	+0.345	+2.584	.013	.010	3	1
UCEC	MSH2 →	-0.198	-1.848	.025	.049	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration

NAP1L4 survival (RNA) · tumor vs normal (RNA) · all NAP1L4 data types