Across TCGA patient cohorts, NAP1L3 mutation is significantly associated with the RNA expression of many other genes, with 3,736 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAP1L3-associated genes across cancer lineages are GZMB, ADNP2, and RNF216. Each is linked with NAP1L3 in more than 2 cancer types. Because this analysis shows association rather than direction, both NAP1L3-to-partner and partner-to-NAP1L3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAP1L3→partner) and Y-score (partner→NAP1L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GZMB →	+1.075	+4.321	<.001	<.001	3	3
UCEC	ADNP2 →	+0.459	+1.939	.001	.008	3	3
UCEC	RNF216 →	+0.330	+1.617	.001	.005	3	3
UCEC	PIMREG →	+0.684	+2.120	<.001	<.001	3	3
UCEC	MAP4K5 →	+0.373	+2.111	.005	.003	3	3
UCEC	INPP5K →	+0.434	+2.716	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,736 associations by consensus.

Exploration

NAP1L3 survival (RNA) · tumor vs normal (RNA) · all NAP1L3 data types