Across TCGA patient cohorts, NAP1L2 mutation is significantly associated with the RNA expression of many other genes, with 4,497 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAP1L2-associated genes across cancer lineages are RAD51AP1, STMN1, and NSL1. Each is linked with NAP1L2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NAP1L2-to-partner and partner-to-NAP1L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAP1L2→partner) and Y-score (partner→NAP1L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAD51AP1 →	+0.658	+2.949	<.001	<.001	3	3
UCEC	STMN1 →	+0.567	+2.650	.002	<.001	3	3
UCEC	NSL1 →	+0.392	+2.928	.003	<.001	3	3
UCEC	EXOSC9 →	+0.539	+3.108	<.001	<.001	3	3
UCEC	PIMREG →	+0.788	+2.436	<.001	<.001	3	3
UCEC	ZCCHC9 →	+0.403	+2.595	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,497 associations by consensus.

Exploration

NAP1L2 survival (RNA) · tumor vs normal (RNA) · all NAP1L2 data types