NAP1L2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NAP1L2 mutation is significantly associated with the total protein of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAP1L2-associated genes across cancer lineages are eIF4E, EGFR_pY1068, and ERK2. Each is linked with NAP1L2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NAP1L2-to-partner and partner-to-NAP1L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAP1L2→partner) and Y-score (partner→NAP1L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMeIF4E →+0.143+1.584.038.03533
UCECEGFR_pY1068 →-0.268-2.378<.001<.00132
UCECERK2 →+0.178+1.662.003.01032
UCECMEK1 →+0.487+2.754<.001<.00132
UCECp21 →+0.143+2.598.020.00532
UCECRab25 →-0.246-1.874.020.04932
Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

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