Across TCGA cell cohorts, NAP1L1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NAP1L1-associated genes across cancer lineages are CFC1, KRTAP12-3, and IQCM. Each is linked with NAP1L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAP1L1-to-partner and partner-to-NAP1L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAP1L1→partner) and Y-score (partner→NAP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CFC1 →	+0.019	+5.539	<.001	.003	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.124	+5.539	<.001	.003	3	1
BLOOD_Leukemia	IQCM →	+0.045	+4.922	<.001	.009	3	1
BREAST	GPR42 →	+0.022	+5.312	<.001	<.001	3	1
BREAST	KRTAP2-2 →	+0.030	+4.781	<.001	.003	3	1
LARGE_INTESTINE	OR4F4 →	+0.025	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

NAP1L1 survival (RNA) · tumor vs normal (RNA) · all NAP1L1 data types