NANP

Across TCGA patient cohorts, NANP mutation is significantly associated with the RNA expression of many other genes, with 243 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NANP-associated genes across cancer lineages are SLC25A51P3, SSXP1, and RNA5SP308. Each is linked with NANP in more than 1 cancer types. Because this analysis shows association rather than direction, both NANP-to-partner and partner-to-NANP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC25A51P3 grouped by NANP-low versus NANP-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NANP→partner) and Y-score (partner→NANP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	SLC25A51P3 →	+0.059	+5.355	<.001	.005	3	2
LIHC	SSXP1 →	+0.161	+6.902	<.001	<.001	3	2
LIHC	RNA5SP308 →	+1.453	+5.758	<.001	.003	3	2
UCEC	RNU6-270P →	+0.505	+4.400	<.001	.006	3	2
LIHC	EEF1A1P40 →	+0.227	+5.758	<.001	.003	3	2
UCEC	RNA5SP276 →	+0.840	+5.414	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 243 associations by consensus.

SLC25A51P3 by NANP expression — LIHC

Explore this box plot interactively →