NANP

Across TCGA cell cohorts, NANP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,337 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NANP-associated GO terms across cancer lineages are Ribosomal protein import into nucleus, mRNA export from nucleus, and DNA-templated transcription termination. Each is linked with NANP in more than 11 cancer types. Because this analysis shows association rather than direction, both NANP-to-partner and partner-to-NANP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal protein import into nucleus grouped by NANP-low versus NANP-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NANP→partner) and Y-score (partner→NANP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Ribosomal protein import into nucleus →	+0.076	+0.441	.001	.007	3	12
LUNG_NSCLC_LUSC	mRNA export from nucleus →	+0.079	+0.555	<.001	.008	3	11
SOFT_TISSUE	DNA-templated transcription termination →	+0.097	+0.538	<.001	<.001	3	10
BONE	Transcription by RNA polymerase I →	+0.091	+0.590	<.001	.001	3	10
LUNG_NSCLC_LUSC	RNA export from nucleus →	+0.083	+0.592	<.001	.004	3	10
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation →	+0.145	+0.820	.006	.004	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,337 associations by consensus.

Ribosomal protein import into nucleus by NANP expression — CNS

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