Across TCGA patient cohorts, NANOS3 mutation is significantly associated with the RNA expression of many other genes, with 163 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NANOS3-associated genes across cancer lineages are SEPTIN14P2, LINC00556, and ILF2P2. Each is linked with NANOS3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NANOS3-to-partner and partner-to-NANOS3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NANOS3→partner) and Y-score (partner→NANOS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SEPTIN14P2 →	+0.288	+3.476	<.001	.003	3	2
COAD	LINC00556 →	+0.344	+3.429	<.001	.003	3	2
BLCA	ILF2P2 →	+0.040	+5.017	.001	.002	3	2
BLCA	MIR4314 →	+0.578	+7.029	<.001	<.001	3	2
UCEC	RN7SKP265 →	+0.216	+4.464	<.001	.005	3	2
UCEC	RNU6-1213P →	+0.406	+5.140	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 163 associations by consensus.

Exploration

NANOS3 survival (RNA) · tumor vs normal (RNA) · all NANOS3 data types