Across TCGA patient cohorts, NANOS3 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NANOS3-associated genes across cancer lineages are NK cells, Macrophages, and Macrophages M1. Each is linked with NANOS3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NANOS3-to-partner and partner-to-NANOS3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NANOS3→partner) and Y-score (partner→NANOS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	NK cells →	+0.009	+5.597	<.001	.040	3	1
UCEC	Macrophages →	+0.025	+3.984	.005	.001	3	1
UCEC	Macrophages M1 →	+0.030	+3.086	.001	.025	3	1
UCEC	MEP →	+0.055	+2.818	.001	.037	1	2

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

NANOS3 survival (RNA) · tumor vs normal (RNA) · all NANOS3 data types