Across TCGA cell cohorts, NANOS1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NANOS1-associated genes across cancer lineages are TEX43, KRTAP12-3, and OR10W1. Each is linked with NANOS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NANOS1-to-partner and partner-to-NANOS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NANOS1→partner) and Y-score (partner→NANOS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TEX43 →	+0.141	+5.969	<.001	.001	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.124	+5.539	<.001	.003	3	1
LARGE_INTESTINE	OR10W1 →	+0.012	+4.977	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

NANOS1 survival (RNA) · tumor vs normal (RNA) · all NANOS1 data types