Across TCGA pan-cancer cohorts, NANOGP9 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of NANOGP9’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where NANOGP9 RNA is repressed in tumor relative to normal tissue. In most cancer types NANOGP9 is over-expressed in tumor, although a few such as BRCA and COAD show the opposite, repressed pattern.
BRCA, COAD, and KIRC are the cancer types where NANOGP9 tumor–normal differential expression is most reproducible.