NANOGP7

Across TCGA pan-cancer cohorts, NANOGP7 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated NANOGP7 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher NANOGP7 RNA is associated with better overall survival. In most high-consensus cancer types, elevated NANOGP7 expression acts as an unfavorable survival marker, although some lineages such as HNSC and ESCA show a favorable association.

HNSC, UCEC, and LGG are the cancer types where NANOGP7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.742	0.594	<.001	114	view →
UCEC	OS	Quartile	III,IV	0.411	0.673	.007	44	view →
LGG	DFS	Tertile	All	0.152	0.414	<.001	42	view →
ACC	OS	Tertile	II,III,IV	0.130	0.681	.003	30	view →
CESC	DFS	Median	All	0.663	0.812	.002	24	view →
LUSC	DFS	Median	IV	0.134	0.827	.014	21	view →
LAML	DFS	Tertile	All	0.409	0.682	.014	12	view →
DLBC	OS	Tertile	II,III,IV	0.640	1.000	.019	9	view →
KICH	DFS	Quartile	All	0.802	1.000	.036	8	view →
PAAD	OS	Quartile	All	0.308	0.600	.004	6	view →
ESCA	DFS	Quartile	All	0.541	0.330	.011	6	view →
LIHC	DFS	Tertile	All	0.350	0.452	.041	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

NANOGP7–HNSC (OS)

Open the HNSC breakdown →