NANOGP3

Across TCGA pan-cancer cohorts, NANOGP3 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated NANOGP3 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher NANOGP3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NANOGP3 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

OV, LUSC, and UCEC are the cancer types where NANOGP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Tertile	II,III,IV	0.250	0.541	.029	90	view →
LUSC	OS	Tertile	II,III,IV	0.213	0.745	<.001	72	view →
UCEC	OS	Tertile	All	0.701	0.878	.003	72	view →
KIRC	OS	Tertile	II,III,IV	0.559	0.800	.003	60	view →
KIRP	DFS	Tertile	All	0.155	0.621	<.001	54	view →
TGCT	DFS	Tertile	All	0.170	0.807	<.001	36	view →
READ	DFS	Tertile	II,III,IV	0.082	0.800	<.001	36	view →
THCA	OS	Tertile	All	0.888	0.994	.005	33	view →
LAML	DFS	Tertile	All	0.181	0.476	.014	18	view →
ESCA	OS	Tertile	III,IV	1.000	0.378	.026	15	view →
STAD	DFS	Tertile	All	0.529	0.668	.044	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

NANOGP3–OV (DFS)

Open the OV breakdown →