Across TCGA pan-cancer cohorts, NANOGP10 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of NANOGP10’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where NANOGP10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NANOGP10 is over-expressed in tumor.
LUAD are the cancer types where NANOGP10 tumor–normal differential expression is most reproducible.