NANOGP1

Across TCGA pan-cancer cohorts, NANOGP1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated NANOGP1 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher NANOGP1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NANOGP1 expression acts as an unfavorable survival marker.

UCEC, COAD, and SKCM are the cancer types where NANOGP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	0.231	0.768	.010	24	view →
COAD	OS	Median	All	0.144	0.799	.001	18	view →
SKCM	DFS	Median	III,IV	0.029	0.597	<.001	11	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

NANOGP1–UCEC (OS)

Open the UCEC breakdown →