NANOGP1

Across TCGA patient cohorts, NANOGP1 mutation is significantly associated with the RNA expression of many other genes, with 88 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible NANOGP1-associated genes across cancer lineages are MIR1179, ATP2B2-IT2, and RNU6-493P. Each is linked with NANOGP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NANOGP1-to-partner and partner-to-NANOGP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1179 grouped by NANOGP1-low versus NANOGP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NANOGP1→partner) and Y-score (partner→NANOGP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR1179 →	+1.171	+7.741	<.001	.009	3	2
LUAD	ATP2B2-IT2 →	+0.089	+7.930	<.001	.008	3	2
LUSC	RNU6-493P →	+0.269	+7.924	.002	.008	3	2
SKCM	OR10Z1 →	+0.034	+5.408	<.001	.002	3	2
COAD	MIR1263 →	+1.494	+7.741	<.001	.009	3	1
COAD	MIR1283-1 →	+0.726	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

MIR1179 by NANOGP1 expression — COAD

Explore this box plot interactively →