NANOGNBP3

Across TCGA pan-cancer cohorts, NANOGNBP3 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated NANOGNBP3 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher NANOGNBP3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NANOGNBP3 expression acts as an unfavorable survival marker, although some lineages such as OV and BLCA show a favorable association.

KIRC, UCEC, and BRCA are the cancer types where NANOGNBP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.555	0.687	<.001	126	view →
UCEC	DFS	Median	All	0.577	0.717	<.001	78	view →
BRCA	DFS	Tertile	All	0.868	0.924	.004	34	view →
OV	OS	Median	II,III,IV	0.359	0.281	.024	26	view →
THCA	OS	Quartile	II,III,IV	0.859	0.983	.006	25	view →
LGG	DFS	Quartile	All	0.642	0.803	.002	15	view →
UVM	DFS	Tertile	III,IV	0.260	0.857	.003	15	view →
CHOL	DFS	Median	All	0.114	0.679	.003	14	view →
BLCA	OS	Quartile	II,III,IV	0.765	0.631	.009	13	view →
GBM	DFS	Tertile	All	0.465	0.229	.013	12	view →
STAD	OS	Quartile	II,III,IV	0.747	0.604	.012	11	view →
KIRP	DFS	Median	All	0.800	0.927	.004	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

NANOGNBP3–KIRC (DFS)

Open the KIRC breakdown →