NANOGNBP2

Across TCGA pan-cancer cohorts, NANOGNBP2 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated NANOGNBP2 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher NANOGNBP2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NANOGNBP2 expression acts as an unfavorable survival marker, although some lineages such as THYM and LUAD show a favorable association.

READ, KICH, and ESCA are the cancer types where NANOGNBP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	All	0.191	0.602	<.001	117	view →
KICH	OS	Tertile	III,IV	0.254	0.791	.008	36	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
HNSC	OS	Tertile	III,IV	0.190	0.679	.002	36	view →
BLCA	OS	Tertile	IV	0.243	0.633	.002	24	view →
SKCM	OS	Tertile	IV	0.415	0.861	.014	18	view →
PRAD	OS	Quartile	All	0.960	0.997	.001	18	view →
MESO	DFS	Quartile	IV	0.068	0.395	<.001	10	view →
PCPG	DFS	Tertile	All	0.331	0.840	.006	9	view →
THYM	DFS	Tertile	All	1.000	0.720	.028	8	view →
LUAD	OS	Median	All	0.408	0.324	.034	4	view →
DLBC	OS	Tertile	All	0.717	0.971	.031	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

NANOGNBP2–READ (DFS)

Open the READ breakdown →